Search results for " thymectomy"

showing 5 items of 5 documents

Bilateral thoracoscopic thymectomy using a novel positioning system.

2013

Several techniques of bilateral video-assisted thoracoscopic extended thymectomy have been proposed, and each has its own proponents. We summarize our experience in 20 patients who underwent bilateral video-assisted thoracoscopic extended thymectomy, using a new patient positioning that amplifies the thoracoscopic view of the cardiophrenic regions which are often difficult to visualize with standard techniques. In all cases, en-bloc thymectomy with complete dissection of the mediastinal fatty tissue was achieved without sternal retractors or additional incisions.

Pulmonary and Respiratory MedicineAdultMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentMyasthenia gravis thoracic surgery video-assisted thymectomy thymus glandMyasthenia graviPatient positioningExtended thymectomyThymus GlandPatient PositioningYoung AdultmedicineHumansVideo assistedThoracoscopic thymectomyvideo-assistedbusiness.industryThoracic Surgery Video-AssistedMedicine (all)General MedicineMiddle Agedmedicine.diseaseThymectomythoracic surgeryMyasthenia gravisSurgeryThymectomySettore MED/18 - Chirurgia GeneraleDissectionCardiothoracic surgerySurgeryFemaleCardiology and Cardiovascular MedicinebusinessHumanAsian cardiovascularthoracic annals
researchProduct

Delayed-type skin reactions in bursectomized or thymectomized chickens.

1977

Chickens can easily be induced to develop delayed-type skin reactions to oxazolone when animals are sensitized 7 days before the challenge. The reaction is quantitated by assessing the increase in wattle thickness: maximum reactions occur 24 h after challenge. The reaction is inhibited by neonatal thymectomy or bursectomy; these findings therefore suggest also an important B-derived component in delayed hypersensitivity to oxazolone.

PharmacologyMaleChemistrymedicine.medical_treatmentOxazoloneCell BiologyThymus GlandDermatitis ContactWattle (anatomy)BursectomyOxazoloneDrug HypersensitivityCellular and Molecular NeuroscienceSkin reactionchemistry.chemical_compoundBursa of FabriciusDelayed hypersensitivityImmunologymedicineMolecular MedicineAnimalsHypersensitivity DelayedMolecular BiologyNeonatal thymectomyChickensExperientia
researchProduct

Uniportal bilateral video-assisted sequential thoracoscopic extended thymectomy

2017

Standard video-assisted thoracoscopic surgery has been reported as a minimally invasive approach alternative to sternotomy for management of myasthenia gravis (MG) associated with thymoma or thymic hyperplasia. Uniportal video-thoracoscopy is an evolution of standard multi-portal video-thoracoscopy for management of several thoracic diseases but its role for resecting mediastinal tumor remains under-evaluated. Herein, we describe our experience with bilateral uniportal thoracoscopic sequential extended thymectomy with case and video illustrations.

uniportal video-assisted thoracic surgery (uniportal VATS)medicine.medical_specialtythymus glandThymomabusiness.industrymedicine.medical_treatmentSettore MED/21 - Chirurgia ToracicaMediastinal tumorExtended thymectomyMyasthenia gravis (MG); thymectomy; thymus gland; thoracoscopic thymectomy; uniportal videoassisted thoracic surgery (uniportal VATS)medicine.diseaseMyasthenia gravisSurgeryThymectomyuniportal videoassisted thoracic surgery (uniportal VATS)Settore MED/18 - Chirurgia Generalethoracoscopic thymectomyMyasthenia gravis (MG)Thoracic diseasesReview Article on Thoracic SurgeryMedicineVideo assistedThoracoscopic thymectomybusinessthymectomy
researchProduct

Surgical treatment of thymoma: personal experience.

2012

Introduction. Thymomas (THs) are rare epithelial tumors of the thymus gland. In this study we report our personal experience in the management and surgical treatment of THs. Case reports. We report two clinical cases treated with combined therapy (surgery followed by adjuvant therapy). Results. Total transternal thymectomy was performed in both patients. The post-operative course was uneventful. The patients received adjuvant radiotherapy and chemotherapy. No relapse has been observed during follow-up. Discussion. THs are usually slowly growing tumors with similar incidence in both sexes. They occur through a wide age range, with a peak in the fifth and sixth decades. Distinctive features r…

MaleSettore MED/18 - Chirurgia GeneraleYoung AdultThymomaSettore MED/21 - Chirurgia ToracicaThymoma thymectomyHumansThymus NeoplasmsAged
researchProduct

Minimal manifestation status and prednisone withdrawal in the MGTX trial

2020

ObjectiveTo examine whether sustained minimal manifestation status (MMS) with complete withdrawal of prednisone is better achieved in thymectomized patients with myasthenia gravis (MG).MethodsThis study is a post hoc analysis of data from a randomized trial of thymectomy in MG (Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone Therapy [MGTX]). MGTX was a multicenter, randomized, rater-blinded 3-year trial that was followed by a voluntary 2-year extension for patients with acetylcholine receptor (AChR) antibody–positive MG without thymoma. Patients were randomized 1:1 to thymectomy plus prednisone vs prednisone alone. Participants were age 18–65 years at enr…

Malemedicine.medical_treatmentAzathioprinelaw.invention0302 clinical medicineRandomized controlled trialPrednisonelawMedicineSingle-Blind Method030212 general & internal medicineYoung adultMiddle AgedThymectomyCombined Modality TherapySubstance Withdrawal Syndrome3. Good healthSettore MED/26 - NEUROLOGIA6.1 PharmaceuticalsAnesthesiaadolescent; adult; animals; combined modality therapy; female; humans; immunosuppressive agents; male; middle aged; myasthenia gravis; prednisone; rats; single-blind method; substance withdrawal syndrome; thymoma; thymus neoplasms; young adult; thymectomyCognitive SciencesFemaleImmunosuppressive Agentsmedicine.drugAdultThymomaAdolescentThymomaClinical Trials and Supportive ActivitiesClinical SciencesMGTX study groupAutoimmune DiseaseArticleYoung Adult03 medical and health sciencesRare DiseasesClinical ResearchMyasthenia GravisPost-hoc analysisAnimalsHumansNeurology & Neurosurgerybusiness.industryNeurosciencesEvaluation of treatments and therapeutic interventionsThymus Neoplasmsmedicine.diseaseMyasthenia gravisRatsThymectomyPrednisoneNeurology (clinical)business030217 neurology & neurosurgeryNeurology
researchProduct